Hives and Swelling
Itchy raised welts that wander around, each lasting less than a day, sometimes with deeper swelling (angioedema). Most follow a virus or have no clear cause and fade within weeks.
The hives ladder
Start at the bottom, climb only if you need to. Hives most days for more than 6 weeks is chronic hives, which is rarely an allergy and usually needs a daily antihistamine at least.
- Step 1 · Self-careCool down and dodge triggersCool showers or packs, loose clothes, and less heat, alcohol and spicy food during a flare.
- Works
- Not tested in trials; eases itch and may cut flares, but won’t stop hives on its own
- Cost
- Free
- How long
- Straight away
- Watch for
- Aspirin and anti-inflammatories can make hives worse. Paracetamol is fine for pain.
Scratching feels great for four seconds, then makes it worse for an hour.
- Step 2 · PharmacyNon-drowsy antihistamine (cetirizine, loratadine or fexofenadine)The main treatment. For hives that keep returning, take it every day, not just when itchy.
- Works
- Settles most short-lived hives; fully controls fewer than half of people with chronic hives at the usual dose
- Cost
- About $10–25 for a month’s supply
- How long
- Works within an hour or two; take daily while hives continue
- Watch for
- Mild drowsiness (more with cetirizine), dry mouth. The old drowsy antihistamines aren’t needed.
Taking it only when itchy is like shutting the gate after the horse has bolted. Daily works better.
- Step 3 · PharmacyHigher antihistamine dose, on medical adviceIf the usual dose isn’t enough, a doctor may advise up to 4 times the usual daily dose.
- Works
- About 6 in 10 not controlled on the usual dose respond to a higher dose (combined trials)
- Cost
- About $30–60 a month
- How long
- 2–4 weeks to judge
- Watch for
- More drowsiness. Only go above the label dose with medical advice.
Same tablet, more of them, with a doctor holding the map.
- Step 4 · PrescriptionMontelukast, or a short course of steroid tabletsMontelukast is sometimes added for chronic hives. Prednisolone is for a severe flare only.
- Works
- Montelukast: small, inconsistent benefit in trials; steroids calm a severe flare fast
- Cost
- Montelukast private script about $20–40 a month; prednisolone under the $25 PBS co-payment, about $10–15
- How long
- Steroids for a few days only
- Watch for
- Montelukast: rarely, serious mood or behaviour changes (including suicidal thoughts) or nightmares; stop and see your doctor. Steroids: poor sleep, mood swings, high sugar; repeated courses cause real harm.
Steroids are a fire extinguisher, not a sprinkler system.
- Step 5 · SpecialistOmalizumab injectionsFor chronic hives not controlled by high-dose antihistamines, from an immunologist or dermatologist.
- Works
- About half to 2 in 3 get good control; about 1 in 3 become hive-free (vs under 1 in 10 on a dummy treatment)
- Cost
- $25 per script on the PBS if criteria are met ($7.70 concession), plus specialist fees
- How long
- Monthly injection; judged at 3–6 months
- Watch for
- Injection-site reactions, headache. Rare allergic reactions, so early doses are given in clinic.
The big gun for chronic hives, and it actually hits the target.
Save your money
Popular, heavily marketed or often asked about, but the evidence is weak or says no.
- Food intolerance tests and elimination dietsFor chronic hives, they rarely find anything except a smaller shopping list.
- Steroid creamsDon’t help hives: the swelling sits too deep and moves too fast. Save the tube for eczema.
- Old sedating antihistamines (e.g. promethazine)No better than non-drowsy ones for hives, and they leave you foggy the next day.
- Vitamin D supplementsSmall trials, mixed results. Worth checking if you’re likely low; not a hives cure.
What you can do
- Cool showers, loose cotton, short nails.
- Paracetamol, not aspirin or anti-inflammatories, for aches.
- Sudden reaction? Note what you ate, took or did in the 2 hours before.
See your GP if
- Hives last more than 6 weeks, or keep coming back
- Swelling happens without hives, especially if you take an ACE inhibitor blood pressure tablet (names end in “-pril”). Antihistamines don’t help this type.
- Individual welts last more than a day, bruise or come with fever or joint pain
Call 000 for swelling of the tongue or throat, trouble breathing or swallowing, a hoarse voice, wheeze, dizziness or collapse. Use an adrenaline autoinjector first if you have one, and lie down rather than stand.
Common questions
What causes hives?
Most cases follow a viral infection or have no clear cause, and settle within days to weeks. Hives most days for more than 6 weeks (chronic hives) is rarely due to allergy.
Which antihistamine is best for hives?
A non-drowsy one such as cetirizine, loratadine or fexofenadine. For hives that keep coming back, take it every day. Only take a higher dose on medical advice; specialist injections (omalizumab) help if that isn’t enough.
Do I need allergy tests for hives?
For chronic hives, allergy tests and strict diets rarely find a cause. Only have them with medical advice.
When are hives an emergency?
Call 000 for swelling of the tongue or throat, trouble breathing or swallowing, a hoarse voice, wheeze, dizziness or collapse. Use an adrenaline autoinjector first if you have one.
How long do hives last?
Each welt usually fades within 24 hours, though new ones can keep appearing. Most bouts of hives settle within days to a few weeks. Hives lasting more than 6 weeks are called chronic hives and often settle by themselves within 1 to 5 years.
Are hives contagious?
No. Hives are a reaction in the skin and can’t be passed on, even when an infection such as a cold triggered them.
Can stress cause hives?
Stress doesn’t usually cause hives on its own, but it can trigger or worsen flares, especially in chronic hives. Heat, tight clothing, alcohol, anti-inflammatories and infections are other common triggers.
Helpful resources
- ASCIA: Hives (urticaria) FAQPatient guide from Australia’s allergy specialists: causes, when testing helps and when it’s an emergency. Free.
- Chronic hives symptom score sheetA 7-day diary (the UAS7) to score hives and itch. Bring it to appointments to show whether treatment is working. Free, NHS.
Evidence and more information
- Healthdirect: Hives
- ASCIA: Hives (urticaria)
- ASCIA: Angioedema
- ASCIA: Chronic hives treatment guideline
- Medicine Today: TGA boxed warning for montelukast
- Br J Dermatol (2016): Higher-dose antihistamines for chronic hives, meta-analysis
maladywise.com/hives/