Fact sheet

Scombroid Fish Poisoning

Flushed, itchy and pounding headache within an hour of eating tuna, mackerel or mahi-mahi? It may be scombroid: histamine from badly stored fish, not a fish allergy. It looks just like an allergic reaction, and antihistamines usually fix it.

It’s not a fish allergy, it’s badly stored fish. Blame the fridge, not your immune system.

Symptoms

How it happens

What helps

Weird but true

Common questions

Is scombroid an allergy?

No. It’s histamine poisoning from fish that wasn’t kept cold enough. Anyone who eats enough histamine can react, and it doesn’t mean you’re allergic to fish.

Which fish cause scombroid?

Mostly tuna, mackerel, mahi-mahi, sardines, anchovies and bonito, which are rich in histidine that bacteria turn into histamine.

Does cooking prevent scombroid?

No. Histamine isn’t destroyed by cooking, canning or freezing. Prevention depends on keeping fish cold from catch to plate.

Helpful resources

Evidence and more information

Updated 14 November 2026. General education, not personal medical advice. Treatment depends on your situation, so talk to your GP or pharmacist.